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refault
[M] shit-stain, w/ diplomatic immunity
 
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3. Related disease

Parkinson's Disease is caused by cell death in the substantia nigra. This cell death may be partly due to oxidative stress. This oxidation may be relieved by neuromelanin. It has been shown that patients with Parkinson's Diseases had 50% the amount of neuromelanin in the substantia nigra as compared to similar patients of their same age but without Parkinson's. The death of neuromelanin containing neurons in the substantia nigra, pars compacta, and locus coeruleus have been linked to Parkinson's Disease and also have been visualized in vivo with Neuromelanin MRI.[4] Neuromelanin has been shown to bind neurotoxic and toxic metals that could promote neurodegeneration. Compared to darker skinned people, White People have lower amounts of neuromelanin. This is why Parkinson's disease and degenerative brain disorders such as dementia are more common among white-skinned populations. Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.[5]
http://en.wikipedia.org/wiki/Neuromelanin

note the link to a distinctly dopaminergic disease, parkinson's.
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Last edited by refault; 12-13-2014 at 03:33 AM..
Old 12-13-2014, 03:20 AM refault is offline  
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