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curdledvomit
 
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this from http://worldnetdaily.com/news/articl...TICLE_ID=47720


OUTBREAK!
Has feared mutation
of avian flu arrived?

Doctors in Thailand, Indonesia see
1st signs of human-to-human spread


Posted: December 2, 2005
10:10 p.m. Eastern





2005 WorldNetDaily.com


Officials in at least two nations now suspect the avian flu bug has mutated into a virus that is being transmitted from human to human a development world health authorities have estimated could result in the deaths of tens of millions.

Thai health officials have expressed concern that the country's two latest confirmed victims may be the beginning of the much feared human-to-human transmission.

Dr. Charoen Chuchottaworn, an avian-flu expert at the Public Health Ministry, said doctors reviewing the cases were alerted by the very mild symptoms present in both patients, neither of whom had had any recent contact with birds or poultry. The doctors are unsure as to how either of the infected contracted the disease and have raised the possibility that the virus has traded its pathogenicity for ease of transmission.

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Old 12-03-2005, 01:32 PM curdledvomit is offline  
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Vienge.
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Hotness, finally this thread is about to pay off.

Everyone board the flu train! WHOO WHOOO
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Old 12-03-2005, 02:00 PM Vienge. is offline  
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Janet Reno
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Wether or not this is for real, i'm sorry for being nasty to you and your passion, curdledidoo.
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Old 12-03-2005, 02:22 PM Janet Reno is offline  
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curdledvomit
 
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Quote:
Originally Posted by Janet Reno
Wether or not this is for real, i'm sorry for being nasty to you and your passion, curdledidoo.

no worries

this from http://www.sciencedaily.com/upi/?fee...ne-birdflu.xml

Breaking News


2,000 birds die in Ukraine

KIEV, Ukraine, Dec. 4 (UPI) -- A state of emergency has been declared parts of southern Ukraine after outbreaks of bird flu were detected in the Crimea peninsula.

Some 2,000 birds have died, reported Xinhua, the government-run news agency.

Ukrainian officials say the dead birds tested positive for the H5 subtype of avian influenza.

Samples have been sent to laboratories in Britain and Italy for further checking to see if the virus is of the highly pathogenic H5N1 strain, which has killed nearly 70 people in Asia since 2003.

The results are expected by Thursday.

The dead birds were from three regions in the Crimea peninsula, including Sovetskiy and Dzhankoysky.

Experts fear the H5N1 virus could mutate into a new type, which could be easily transmitted among humans and cause a pandemic.

Copyright 2005 by United Press International. All Rights Reserved.
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Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-04-2005, 10:59 PM curdledvomit is offline  
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curdledvomit
 
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this from http://www9.sbs.com.au/theworldnews/...26237&region=2



MORE HUMAN FLU IN CHINA
9.12.2005. 13:27:29

China has announced a fifth human case of bird flu, as early results showed the deadly H5N1 strain of the virus was present in Ukraine.
Xinhua news agency said a 31-year-old female farmer fell ill with pneumonia-like symptoms after contact with dead birds in the northern Liaoning province, where there has been an outbreak of the disease among birds.

"The Ministry of Health reported on December 8 that a pneumonia case of unknown reason in Heishan county, Liaoning province, has been confirmed as deadly H5N1 bird flu," Xinhua said.

Following treatment at a hospital, the woman recovered and was discharged on November 29.

There have been two deaths among China's other four bird flu cases. A 10-year-old girl is currently undergoing emergency treatment for the disease in the southern region of Guangxi after falling ill on November 23.

It was unclear how she contracted the virus and investigations were ongoing.

The lethal H5N1 strain of bird flu has claimed almost 70 human lives in Asia since late 2003.

Thirty H5N1 outbreaks among birds have been confirmed across China this year.

The World Health Organisation (WHO) warned on Wednesday that more outbreaks were likely in China over the next few weeks.

China is seen as a potential flashpoint for a feared global pandemic because it has the world's biggest poultry population and is on three major global routes taken by migratory birds.

Ukraine tests

The lethal H5N1 strain is suspected in poultry that died en mass in the northeast corner of Ukraine's Crimea peninsula last week, according to preliminary test results.

Ukraine's former chief veterinary inspector, Pyotr Verbitsky, said preliminary results from a Russian lab showed the presence of H5N1.

"But the tests continue and tomorrow it will be known for certain," Interfax quoted Dr Verbitsky as saying.

President Viktor Yushchenko fired the chief vet this week for what he said was un-preparedness for a bird flu outbreak.

Mr Yushchenko declared a state of emergency in the affected areas of Ukraine's southern peninsula in the Black Sea and the villages where the H5 virus has
been confirmed have been placed under quarantine.

The poultry is thought to have contracted the virus from wild birds, millions of which use the nearby Sivash saltwater lake as either a wintering site or a stopover point on their winter migration route.

In Asia meanwhile, North Korea was to begin quarantining people with high fevers because of concerns over a possible bird flu outbreak, a South Korean news report said.

Pyongyang would step up quarantines to check airline attendants and sailors coming from overseas for symptoms of bird flu.

North Korea has reported no outbreaks of bird flu this year, but its reclusive leader Kim Jong-Il himself issued a rare public call in November for concrete precautions to prevent the disease.

Vaccines hampered

As countries in Europe and Asia stepped up bird flu monintoring, a British virologist says efforts to control the spread of bird flu in Southeast Asia were being hampered by the use of ineffective and often fake agricultural vaccines.

Such animal vaccines could be increasing the threat of the virus evolving and being able to pass to humans, US-based WHO animal flu specialist Robert Webster said.

He has called for more rigorous minimum standards for agricultural vaccines.

"There are good vaccines and bad vaccines. Good vaccines reduce virus load; bad vaccines stop the signs of disease but the virus keeps replicating, spreading and evolving," he told reporters in London.

In Asia, the potentially deadly H5N1 strain has already split into as many as five different lineages, he said.

Drug production boosted

Swiss drug giant Roche Pharmaceuticals has made agreements with 15 laboratories in the US to produce extra quantities of its Tamiflu medicine to counter avian flu.

US Senator Charles Schumer said Roche which holds the exclusive rights to manufacturing Tamiflu was about to announce the accords, but he said the deal depends on the US government and other countries making firm orders for the drug.

Mr Schumer urged the US administration and Congress to act quickly to vote money to build a stocks of Tamiflu, considered the most effective drug to counter H5N1.
__________________
how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-08-2005, 08:46 PM curdledvomit is offline  
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this from http://today.reuters.com/News/Crises...ryId=L09731805

Tests confirm infected Romanian turkey has H5N1
Fri 9 Dec 2005 10:13 AM ET
LONDON, Dec 9 (Reuters) - Tests on an infected Romanian turkey have confirmed that the bird had the deadly H5N1 strain of avian flu, British officials said on Friday.

Romania last month sent a turkey to Britain for further tests after it was found to have a form of avian flu. The bird was from the small village of Scarlatesti in Braila county, some 70 miles (110 km) west of the area where the virus was first detected in the Danube delta in October.
__________________
how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-09-2005, 09:27 AM curdledvomit is offline  
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this from http://www.forbes.com/technology/ebu...ap2382920.html


Update 3: Government Tests Readiness for Pandemic
12.10.2005, 03:20 PM

After role-playing an outbreak of pandemic flu, federal officials said Saturday that saving lives and containing the economic damage will require more planning in local communities and increased production of vaccines and medications.

"This is a time for us to be informing but not inflaming. It's a time for us to inspire preparation but not panic," Health and Human Services Secretary Mike Leavitt told reporters at the White House. About 20 Cabinet secretaries and government officials spent four hours testing the government's readiness for any flu outbreak.

"We have time to become the first generation, literally, in the history of man to do something to be prepared for a pandemic," Leavitt said.

President Bush's homeland security adviser, Fran Townsend said that in the little time left before lawmakers adjourn for the year, Congress should approve the $7.1 billion in emergency flu preparedness funds that the president has requested.

But the prospects for the request are not clear, as conservatives in the House oppose rubber-stamping it without finding spending cuts elsewhere in the budget. Senate Majority Leader Bill Frist, R-Tenn., has advocated for the money.

"Days matter," said White House deputy press secretary Trent Duffy.

Though in town for the weekend, the president did not participate in the drill. While it was going on around a C-shaped table in a large room in the White House complex, Bush left for nearby suburban Maryland to ride his mountain bike for more than an hour. Vice President Dick Cheney was in his White House office for part of the time, but also did not attend.

Duffy said Bush would be briefed in detail, but didn't need to take part because his role as director of the effort to prepare and respond is already well-defined.

"The president's been focused on this for years," he said. "It is impossible to have the kind of candor and open discussion and a useful preparedness exercise with the president and/or the vice president in the room."

Fears of a pandemic have increased as a virus infecting millions of birds has spread throughout Asia and parts of Europe. While bird flu has not yet appeared in the United States, or spread from person to person, officials worry it could mutate and - because humans have no immunity to it - become as contagious globally as the annual flu.

So far, the virus has killed about half of the 120 people who have contracted it, all as a result of close contact with poultry.

The administration is working under the worst-case assumption that as many as 90 million Americans would become sick and 2 million would die during a worldwide flu pandemic, which could be caused by the bird flu or another strain. A moderate pandemic would kill about 209,000.

Officials would not describe the real-world but hypothetical scenarios, modeled by emergency preparedness experts based on previous pandemic outbreaks in the United States, that were used to drive the exercise or the discussions they inspired. Duffy would say only that it was "a very thorough" exercise, and that it wasn't the first that had been conducted by the federal government.

Townsend said the drill confirmed that the most important part of the administration's plan for getting ready for any outbreak is looking for ways to speed the production of vaccines and stockpiling more of the antiviral Tamiflu, which can reduce the severity of the disease if taken early enough.

Another linchpin is the role of state and local governments, officials said afterward. Leavitt plans to travel to all 50 states to coordinate and boost pandemic preparation.
__________________
how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-11-2005, 07:56 AM curdledvomit is offline  
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fiveohnoes
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We're all gonna die aren't we.

Good game America, we had some fun huh?
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1-3-7-2-6-5-4-8 > 1-8-7-2-6-5-4-3 :D

Originally Posted by Lantec
How does the waxing process work? Do you have to use one of those mechanical circle things?
Old 12-11-2005, 09:20 AM fiveohnoes is offline  
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IMNobody IV
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dont think i have the bird flu but last week i had strep throat and i never fully recovered from that and it turned into pneumonia
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Old 12-11-2005, 09:24 AM IMNobody IV is offline  
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Contrary to my previous title I never fucked Inf's mother
 
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Roche is granting the right to make tamiflu to half a dozen competitiors, not for free of course.
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http://www.genmay.com/showthread.php?t=572323
Old 12-11-2005, 09:33 AM TheMorlock is offline  
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how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-12-2005, 06:05 PM curdledvomit is offline  
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This bird flu needs to hurry up and kill everyone.
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Thanks.
Old 12-12-2005, 06:07 PM antisechs is offline  
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dude, I've got a phd in viral immunology and even I'm not this obsessed with this story

I'm extremely interested in it, just not to the creepy extent you are
Old 12-12-2005, 06:10 PM Viremia is offline  
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this from http://www.cdc.gov/ncidod/EID/vol12no01/05-1370.htm

Policy Review

Nonpharmaceutical Interventions for Pandemic Influenza, International Measures

World Health Organization (WHO) Writing Group1

Suggested citation for this article

Since global availability of vaccine and antivirals against influenza caused by novel human subtypes is insufficient, the World Health Organization (WHO) recommends nonpharmaceutical public health interventions to contain infection, delay spread, and reduce the impact of pandemic disease. Virus transmission characteristics will not be completely known in advance, but difficulties in influenza control typically include peak infectivity early in illness, a short interval between cases, and to a lesser extent, transmission from persons with incubating or asymptomatic infection. Screening and quarantining entering travelers at international borders did not substantially delay virus introduction in past pandemics, except in some island countries, and will likely be even less effective in the modern era. Instead, WHO recommends providing information to international travelers and possibly screening travelers departing countries with transmissible human infection. The principal focus of interventions against pandemic influenza spread should be at national and community levels rather than international borders.

Pandemic preparedness ideally would include pharmaceutical countermeasures (vaccine and antiviral drugs), but for the foreseeable future, such measures will not be available for the global population of >6 billion (1). Thus, in 2005, after consultations with experts, the World Health Organization (WHO) recommended nonpharmaceutical public health interventions in its updated global influenza preparedness plan (2). The recommendations are intended as guidance, not as formal WHO advice (3). Such interventions, designed to reduce exposure of susceptible persons to an infectious agent, were commonly used for infection control in previous centuries. This report (part 1) and a companion article (part 2 [4]) summarize the scientific data, historic experience, and contemporary observations that make up the limited evidence base for these interventions as applied to influenza. Part 1 summarizes the relevant transmission characteristics of influenza and the basis for interventions to prevent spread from 1 country to another; part 2 summarizes the basis for measures within countries at the national and community levels. Both parts are designed to be read in conjunction with WHO recommendations (2,3).

Nonpharmaceutical interventions outside of healthcare settings focus on measures to 1) limit international spread of the virus (e.g., travel screening and restrictions); 2) reduce spread within national and local populations (e.g., isolation and treatment of ill persons; monitoring and possible quarantine of exposed persons; and social distancing measures, such as cancellation of mass gatherings and closure of schools); 3) reduce an individual person's risk for infection (e.g., hand hygiene); and 4) communicate risk to the public. We discuss the first category; categories 2 and 3 are addressed in part 2. We do not address infection control measures for patient care or risk communication.

Transmission Characteristics of Influenza Viruses

Most information on transmission of influenza viruses is based on older experimental studies, inference from observations during outbreaks, and studies with other objectives, especially the assessment of vaccine or drug efficacy. These sources have substantial limitations: investigations often used different methods, involved small numbers of persons, and reflected the behavior of influenza A and B viruses in seasonal rather than pandemic settings (the level of preexisting immunity in populations is substantially higher in seasonal epidemics). For this reason, data from young children, who presumably lack prior exposure and therefore immunity to influenza, may better reflect illness and viral shedding patterns of pandemic disease. In many studies, the preexisting influenza antibody status of study participants is not reported, even though this factor is critical in influencing illness and viral shedding patterns. In addition, in controlled studies, in which susceptible study participants are typically screened for preexisting influenza antibody by hemagglutination inhibition assays to the challenge virus, the routes of infection and the challenge virus can differ. Other factors that differ among studies are the age and preexisting medical conditions of study participants and the timing of specimen collections for virus testing. The "infectiousness" of patients is virtually always inferred on the basis of viral shedding from the upper respiratory tract rather than from directly observed transmission, but the relationship between nasopharyngeal shedding and transmission is uncertain and could vary. Detailed studies of lower respiratory tract virus loads, particularly relevant to small-particle aerosol transmission during coughing and sneezing, are not available.

Viral Shedding and Transmission by Persons with Symptoms

In otherwise healthy adults with influenza infection, viral shedding 2448 h before illness onset has been detected but generally at much lower titers than during the symptomatic period (Appendix). Titers of infectious virus peak during the first 2472 h of illness (103107 50% tissue culture infective dose [TCID50]/mL nasopharyngeal wash) and decline within several days, with titers usually low or undetectable by day 5. Shedding in highly immunocompromised persons may last weeks to months. Compared with adults, children can shed virus earlier before illness begins and for longer periods once illness starts. As in adults, peak shedding in children occurs during the first 13 days of illness, but absolute levels may be higher than those in adults. In 1 report, at least 4 illnesses (8% of the total) in children were associated with presymptomatic shedding that began 6, 4, 3, and 3 days, respectively, before illness onset (5). The median duration of virus detection is typically 78 days after illness onset, but shedding for up to 21 days has been recorded. In 1 study, virus was shed by 10% of children on days 811, by 5% on days 1215, and by 0% on days 1619 (6). Infants with infection requiring hospitalization may shed virus longer. In both adults and children, shedding does not usually continue once illness has resolved. Serologic testing indicates that ≈30%50% of seasonal influenza infections may not result in illness.

Viral Shedding and Transmission by Infected Persons without Symptoms

During the incubation period, persons with presymptomatic influenza infection shed virus at lower titers than persons with symptoms (Appendix); however, the infectiousness of those with presymptomatic infection has not been studied. Apparently the only published report implicating transmission during the incubation period involves a group of adults in New Zealand in 1991. Of 26 adults who bagged fertilizer for 8 h, influenzalike illness (fever, headache, sore throat, myalgia, respiratory symptoms) developed in 16 and mild, "cold-like" illnesses developed in 3 persons within 24 to 48 h after working with the fertilizer. A person considered to be the probable index patient had felt unwell during work, although he did not have respiratory symptoms; an influenzalike illness began to develop 6 h after he finished work. Influenza A virus H1N1 was isolated from 2 symptomatic persons; whether these included the suspected index patient and whether that person transmitted infection during an incubation period or the cluster resulted from community exposure are unknown. The group shared drinking bottles and worked in a dusty environment, both of which could have facilitated transmission (7).

Large-Droplet and Aerosol Respiratory Transmission

Animal studies and most influenza outbreaks among humans suggest that virus-laden large droplets (particles >5 mm in diameter) generated when infected persons cough or sneeze are the predominant mechanism of influenza virus transmission (8). However, evidence for aerosol spread (especially in unventilated conditions) is available (9). Although a direct comparison has not been made, experimental studies suggest that the infectious dose for humans exposed by aerosol is lower than that seen with experimental nasopharyngeal instillation (10). The precise proportion of infections transmitted by large droplets versus aerosols is difficult to assess and likely depends on the setting but is relevant when developing recommendations on mask use. Data do not exist to quantify the relative efficacy of surgical masks versus respirators in preventing influenza infections in exposed persons, but surgical masks should protect against large droplets, believed to be the major mode of transmission (8).

Transmission by Contaminated Hands, Other Surfaces, or Fomites

Transmission of influenza viruses by contaminated hands, other surfaces, or fomites has not been extensively documented but is believed to occur. In a nursing home outbreak in Hawaii, an investigation concluded that transmission of oral secretions from patient to patient by staff who were not gloved best explained the outbreak (11). In an environmental survival study, influenza A virus placed on hard, nonporous surfaces (steel and plastic) could be cultured from the surfaces at diminishing titer for <24 to 48 h and from cloth, paper, and tissues for <8 to12 h at conditions of 35% to 40% humidity and a temperature of 28C (12). Higher humidity shortened virus survival. Virus on nonporous surfaces could be transferred to hands 24 h after the surface was contaminated, while tissues could transfer virus to hands for 15 min after the tissue was contaminated. On hands, virus concentration fell by 100- to 1,000-fold within 5 min after transfer. The authors concluded that transmitting infection from the surfaces tested would require a high titer of virus (105.0 TCID50/mL) on the surface; such titers can be found in nasal secretions at an early stage of illness.

Incubation Period and Infectiousness



lots more to read but its scary...

also notice the date, this is out ahead of print.
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how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-12-2005, 06:10 PM curdledvomit is offline  
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curdledvomit
 
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Quote:
Originally Posted by Viremia
dude, I've got a phd in viral immunology and even I'm not this obsessed with this story

I'm extremely interested in it, just not to the creepy extent you are



__________________
how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 12-12-2005, 06:11 PM curdledvomit is offline  
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