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this from http://www.dailymail.co.uk/pages/liv...n_page_id=1774


The vaccine to cure every strain of flu

by FIONA MacRAE Last updated at 22:20pm on 28th December 2006

British scientists are on the verge of producing a revolutionary flu vaccine that works against all major types of the disease.
Described as the 'holy grail' of flu vaccines, it would protect against all strains of influenza A - the virus behind both bird flu and the nastiest outbreaks of winter flu.
Just a couple of injections could give long-lasting immunity - unlike the current vaccine which has to be given every year.
The brainchild of scientists at Cambridge biotech firm Acambis, working with Belgian researchers, the vaccine will be tested on humans for the first time in the next few months.
A similar universal flu vaccine, being developed by Swiss vaccine firm Cytos Biotechnology, could also be tested on people in 2007 - and the vaccines on the market in around five years.
Importantly, the vaccines would also be quicker and easier to make than the traditional jabs, meaning vast quantities could be stockpiled against a global outbreak of bird flu.
Martin Bachmann, of Cytos, said: "You could really stockpile it. In the case of a pandemic, that would be a huge advantage.
"If you were to start making a traditional vaccine at the start of a pandemic, there is no way there would be enough."
The Government believes a bird flu pandemic is inevitable, killing 50,000 people in Britain alone.
However, it acknowledges that the bug could be much more lethal - infecting one in two people and claiming more than 700,000 lives.
Normal winter flu can also kill, claiming up to 12,000 lives a year in the UK.
Although a vaccine exists, constant changes in the virus's appearance have until now made it impossible to create just one flu vaccine. Instead a new vaccine is put together each year to protect against the particular strains circulating at that time.
In addition, the virus used in the jab is grown in hen's eggs - a time-consuming process that yields just one shot of vaccine per egg.
The new jabs would be grown in huge vats of bacterial 'soup', with just two pints of liquid providing 10,000 doses of vaccine.
Current flu vaccines focus on two proteins on the surface of the virus. However, these constantly mutate in a bid to fool the immune system, making it impossible for vaccine manufacturers to keep up with the creation of each new strain.
The universal vaccines focus on a different protein called M2, which has barely changed during the last 100 years.
The protein is found in all types of Influenza A, including the current bird flu and the virus that caused the 1918 Spanish flu pandemic which killed up to 50 million across the globe.
Normally, such vaccines would have to go through at least five years of human tests before going on the market. However, if a bird flu pandemic occurs before that, they could be made more quickly available.
Zurich-based Cytos, which is also developing anti-smoking and obesity vaccines, has showed that its version of the jab stops mice dying from a dose of flu strong enough to kill them four-times over.
The vaccinated animals were also spared the fever that normally goes along with flu.
Although it is too early to say what the effect would be in humans, an initial course of two or three shots could provide long-lasting immunity, topped up with booster shots given every five to ten years.
Dr Ashley Birkett, of Acambis, said: "It wouldn't be that one shot protects for life but you would need fewer doses over your lifetime."
In addition, the jabs could be produced in vast quantities and stockpiled ahead of a flu pandemic - or even given to people in advance.
In contrast, a traditionally-produced vaccine, matched to the specific strain of flu, would not be available until around six months after the start of the pandemic.
The new vaccines only protect against influenza A - the version of the bug responsible for pandemic flu and the most severe cases of winter flu.
However, it may also be possible to create a similar jab against influenza B, which causes a milder form of winter flu.
Professor John Oxford, Britain's leading flu expert, said the development of a universal vaccine was the "holy grail" of flu research.
He added: "If you get a M2 vaccine which protects against the whole caboodle in the same vaccine, the possibilities are huge."
But, others cautioned that there is no guarantee that the jabs would be as effective in humans as it has been in animals.
Virologist Professor Ian Jones, of the University of Reading, said: "It is an encouraging technique which may have a role to play but it is too soon to assume that it will translate into a universal vaccine in the human population."
Dr Jim Robertson, a vaccine expert from the government-funded National Institute for Biological Standards and Control, said the main advantage of a universal jab would be lasting immunity.
"If it works, it will be lovely," he said. "The best result would be that it would last for a long, long time."
Dr Ron Cutler, an infectious diseases expert from the University of East London, said: "Continual protection would be a tremendous advantage against flu."
He cautioned however, that there is no guarantee that the M2 protein will not mutate in the future - meaning the jab will have to be regularly reformulated.
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Old 12-28-2006, 09:16 PM curdledvomit is offline  
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stop this fucking thread
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Old 12-28-2006, 09:18 PM Totally Awesome is offline  
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im still waiting to die
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Old 12-28-2006, 09:21 PM dildérto is offline  
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shit scientists going to breed a new superflu with that
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Old 12-28-2006, 09:31 PM TheMorlock is offline  
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where the fuck is this shit
give it to me
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Old 12-28-2006, 09:33 PM aoeoae is offline  
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Quote:
Originally Posted by TheMorlock View Post
shit scientists going to breed a new superflu with that

thats kinda what i was thinking...some nasty virius thats immune to it
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Old 12-28-2006, 09:46 PM curdledvomit is offline  
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stop this fucking thread
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Old 12-28-2006, 09:48 PM firewars is offline  
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Quote:
Originally Posted by curdledvomit View Post
thats kinda what i was thinking...some nasty virius thats immune to it
unlike bacteria
99% of the protein coat of a virus is for mere survivability between hosts. yet our immune system keys on (random segment per virus)these proteins because if our immune system keyed on the area of the protein coat that the virus uses to activate our cell walls with for entry we would develop an immune disorder. (things that make you go hmmmm)

Unless M2 is used as a lock/key area for invasion of the cell this vaccine will be a disaster
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Last edited by TheMorlock; 12-28-2006 at 09:57 PM..
Old 12-28-2006, 09:53 PM TheMorlock is offline  
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Bird flu is the next Spanish flu. If you read the scientific reports, the magnitude of the threat quickly emerges.

That doesn't stop the media from covering it up to prevent panic, though.
Old 12-28-2006, 10:28 PM aoeoae is offline  
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Quote:
Originally Posted by aoeoae View Post
Bird flu is the next Spanish flu. If you read the scientific reports, the magnitude of the threat quickly emerges.

That doesn't stop the media from covering it up to prevent panic, though.

umm H5N1 has been shown to be almost identical to the pandemic spanish flu in its major aspects.

Wich means there is going to be lots of land in africa, mexico the greater arab states china and india once it crosses to human human trasnfer
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Old 12-28-2006, 10:34 PM TheMorlock is offline  
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this from http://www.ireland.com/newspaper/bre...breaking10.htm


Last Updated: 05/01/2007 08:21

WHO chief issues bird flu warning


The new boss of the World Health Organisation (WHO) has renewed the agency's warning that the world must keep up its guard against bird flu.
Dr Margaret Chan holds the most prominent United Nations post ever filled by a Chinese national. Dr Chan said there had been a lull in bird flu infections in recent months, but that cases had begun picking up again in the last few weeks.
"This H5N1 (virus strain) is causing unprecedented damage to the poultry sector, and along the way many people were infected, and more than half of these people died," Dr Chan said.
"We must not let our guard down. We must maintain our vigilance." She said the world was gearing up to improve surveillance of the disease and rapid response to any outbreaks.
More also needed to be done against older diseases, such as malaria, Mr Chan said. "We are taking a new look at how to deal with this very tenacious killer," Mr Chan said.
"We have the tools, but we need to understand why we are not making progress."
Some 3,000 children in Africa die from the disease every day, she said. The agency has in the past been criticised for its inconsistent advice regarding malaria control, resulting in an increase in cases.
The WHO also intends to press on with its campaign to eradicate polio, even though it missed its original target of eradicating the disease worldwide by 2000.
Dr Chan is likely to be rated on how well she can get the Chinese government to co-operate with global efforts to contain infectious diseases like bird flu.
China has been criticised for dragging its feet in reporting outbreaks to WHO and supplying virus samples to the global health community for analysis.
She said she remained the best qualified person to obtain Chinese co-operation, but she declined to say when she expected her efforts to bring results.
Dr Chan, a 59-year-old from Hong Kong, defeated a field of 12 other candidates to become director-general in a vote by WHO member countries in November. Her term will run until June 30th 2012. The agency has a two-year budget of $3.3 billion.
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Old 01-05-2007, 05:30 PM curdledvomit is offline  
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this from http://www.tass.ru/eng/level2.html?N...8278&PageNum=0


Bird death of H5N1 virus confirmed in Hong Kong


08.01.2007, 00.29


HONG KONG (XIANGGANG), January 8 (Itar-Tass) -- The avian influenza strain dangerous for humans has again been traced amongst wild birds in Hong Kong.
Laboratory tests confirmed H5N1 virus in the bloodstream of a small bird found dead in a densely populated area several days ago, the South China Morning Post said on Sunday.
This is the first confirmed case of wild birds’ influenza in Hong Kong since last March. Sanitary services have reminded local residents of the need to avoid contacts with birds. It is prohibited to feed doves, and the violation will be punished with a large fine.
Early last year the authorities prohibited private farmsteads to raise chickens, geese and ducks.
The first outbreak of avian influenza happened in Hong Kong in 1997 and killed six people. The new H5N1 case shows that the infection persists in the local fauna.
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how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 01-08-2007, 07:15 AM curdledvomit is offline  
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jesus christ....

how much are you paying the mods not to lock this shit thread?
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Old 01-08-2007, 07:19 AM The-Raven is offline  
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Quote:
Originally Posted by Sickfuckingcreepystalke View Post
jesus christ....

how much are you paying the mods not to lock this shit thread?

No shit. Its nothing but media hype. You don't even hear about it on the news anymore. Not for a long time. It was a short period of time where people freaked about it. Then everyone calmed down and forgot about it.

because its pointless
Old 01-08-2007, 07:21 AM Kahnza is offline  
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i this thread. it's so lame, and so was the bird flu when EVERYONE was talking about it. keep up the good work. you have made the legion of [M] reporters proud, by keeping us updated w/up to the minute news and reports. gj




edit: i was beating up the chicken in the barn, while playing majora's mask last night. i got bored pretty quick, so i didnt hit it enough to see if i'd get attacked by a flock once i did

real edit: NEIN! to the lock! we must be prepared for the outbreaks!!!!!
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Last edited by dirty sanchez; 01-08-2007 at 07:25 AM..
Old 01-08-2007, 07:23 AM dirty sanchez is offline  
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