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curdledvomit
 
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this from http://www.kansascity.com/mld/kansas...s/15889504.htm


BIRD FLU | Variant takes hold in Asia

H5N1 mutates into new strain

A vaccination program may have helped accelerate the new variant of bird flu.


Cox News Service


ACHMAD IBRAHIM | THE ASSOCIATED PRESS
A man selling ducks waited for customers earlier this month in Jakarta, Indonesia. The country said it would begin to clear residential areas of chickens and ducks as part of its fight against bird flu. Meanwhile, a new strain of bird flu has sprung up in China.

WASHINGTON | A new strain of the H5N1 influenza virus has emerged in China, scientists said Monday.
The strain is poised to cause another global wave of infection among birds and the human beings who come into close contact with them.
The new “bird flu” variant does not appear at this point to pose a greater risk to humans than earlier strains, said a leading influenza expert, Robert Webster of St. Jude Children’s Research Hospital in Memphis, Tenn.
But he added that the emergence of the new strain shows that H5N1 is still mutating, a process that experts fear could eventually convert it into a form capable of causing a deadly and freely spreading human disease.
“It would probably take an accumulation of many changes like this for a virus that is capable of spreading among human beings to develop, but it is continuing to drift and continuing to evolve,” Webster said in a telephone interview.
The new form of the virus has become the primary version of the bird flu in parts of China and has spread to Hong Kong, Laos, Malaysia and Thailand, Webster and scientists at the University of Hong Kong reported in an article in the Proceedings of the National Academy of Sciences.
Webster said scientists believe that 23 human cases known to be caused by the new strain of virus — all in China except for one in Thailand — came from direct contact with infected poultry.
Webster and his colleagues reported that they tracked the appearance and spread of the new strain by monitoring fowl sold in live poultry markets in urban areas of southern China.
He said samples of the new strain have been turned over to the World Health Organization and the Centers for Disease Control and Prevention for use in updating preliminary vaccines being stockpiled for emergency use in the event of a human pandemic.
Frederick Hayden, a University of Virginia virologist working full time with the World Health Organization’s pandemic preparedness program, said the variant strain appears to have “escaped” from a compulsory poultry vaccination program instituted in China last year. The program may have killed off competing versions of the virus and allowed this one to spread faster, he said.
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Old 10-31-2006, 06:08 AM curdledvomit is offline  
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Inf
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Just kill all birds and be done with it.
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Old 10-31-2006, 06:15 AM Inf is offline  
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ERL857
 
wow this thread is still alive

edit: but apparently some birds and other creatures aren't
Old 10-31-2006, 07:24 AM ERL857 is offline  
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Originally Posted by Knox View Post
This thread is so fucking lame.


Old 10-31-2006, 07:39 AM sir tex is offline  
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this from http://www.medicalnewstoday.com/heal...p?newsid=55492


Vaccine Resistant H5N1 Bird Flu Spreads In South East Asia


It emerged in China and is spreading in southeast Asia - a new H5N1 bird flu strain which is highly resistant to current vaccines. The way this virus is evolving means our current measures are probably ineffective, according to Dr. Yi Guan, Director, State Key Laboratory of Emerging Diseases, Hong Kong, in a new report.

You can see the report in the Proceedings of the National Academy of Sciences.

Dr. Guan, and team, say the new strain is gradually becoming the dominant one in south east Asia. They believe the new strain has started a third H5N1 infection wave in southern China, as well as making headway into Hong Kong, Laos, Malaysia, and Thailand. The new strain is taking hold because current vaccines used to protect poultry from H5 infection are much less effective against it.

Several humans have been infected with this new strain, says the report. At the moment it is spreading from rural into urban areas, where efforts to stem its spread will be much more challenging.

The report states that current poultry vaccination methods must be addressed. We cannot rely on a single vaccine over a number of years, as has been the case. Even though the vaccination of all chickens in China is mandatory, the program will not stop the spread of this new strain, which could easily make its way to other parts of the world. If more chickens become infected, so will more humans.

Guan stressed that systemic influenza surveillance of poultry over affected regions must be thorough. "By doing this, we will be able to determine the dynamics of the spread of this virus," he said. "It is also possible that poultry vaccines may need to be tailored to effectively neutralize the particular strain of virus that is present in a particular region."

Several scientists say that thorough surveillance programs will help us eventually come up with a broad-spectrum vaccine - one that may work for many H5 strains.

"Emergence and predominance of an H5N1 influenza variant in China"
G. J. D. Smith , X. H. Fan , J. Wang , K. S. Li , K. Qin , J. X. Zhang , D. Vijaykrishna , C. L. Cheung , K. Huang , J. M. Rayner , J. S. M. Peiris , H. Chen , R. G. Webster , and Y. Guan
Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0608157103
Click here to see abstract online

Written by: Christian Nordqvist
Editor: Medical News Today
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Old 11-01-2006, 07:55 AM curdledvomit is offline  
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this was locked for a reason you moron. a fie on your house
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Old 11-01-2006, 08:52 AM The-Raven is offline  
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Quote:
Originally Posted by Sickfuckingcreepystalke View Post
this was locked for a reason you moron. a fie on your house

I have been really good about not replying to trolls but i will make an exception here...STFU 5k.



edit: if you don't want to read it then don't fucking click you asswidget
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Old 11-01-2006, 12:18 PM curdledvomit is offline  
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this from http://news.nationalgeographic.com/n...-bird-flu.html

New Bird Flu Strain Spreads Fast, Is Resistant to Vaccine

Brian Handwerk
for National Geographic News

November 1, 2006
A newly discovered bird flu strain has emerged in China and has spread rapidly through poultry in Southeast Asia.
Human infections by the new strain have also turned up in several locations, including both farms and urban centers, intensifying fears of a worldwide flu pandemic that could kill millions. (Related: "Bird Flu Will Reach U.S. and Canada This Fall, Experts Predict" [March 14, 2006].)
Magnifying those concerns is the vaccine-selective nature of the new strain, which means that existing animal vaccines are less effective on it than they are on previously known bird flu types.
"This virus seemed to spread very fast over a big geographic region," said Yi Guan, director of the State Key Laboratory of Emerging Infectious Diseases at the University of Hong Kong in China.
A team led by Guan discovered the new strain—dubbed "Fujian-like"—while monitoring chickens, ducks, and geese in Chinese markets, including several in Fujian Province (map of China).
"However, we don't have any evidence to show whether this virus is more dangerous or less dangerous than any other H5N1 [bird flu] viruses," Guan said.
He and his colleagues report their findings in this week's issue of the Proceedings of the National Academy of Sciences.
Establishing Dominance
To help prevent the spread of bird flu, China has instituted an extensive, compulsory vaccination program for chickens.
But the effort has proven unable to contain the new strain, which has displaced other H5N1 variants to become the dominant strain in the southern China surveillance area, Guan says.
The new virus accounted for 95 percent of the infected birds that Guan's team examined between April and June 2006.
"This novel variant may have become dominant ... because it was not as easily affected as other strains by the avian vaccine used to prevent H5 infection," Guan said.

"This [means] that H5 avian vaccines are not able to prevent infection by this virus as efficiently as they do with other types of H5N1." Scientists fear that the new strain may have arisen in response to over-reliance on the sole existing bird flu vaccine. "It is not surprising that H5N1 continues to evolve," said Hon Ip, a diagnostic virologist at the U.S. Geological Survey's National Wildlife Health Center in Madison, Wisconsin, who is not affiliated with the new research.
"It is a virus that is looking for opportunities, and this is a good example of how, if there is a weakness, Mother Nature somehow is going to exploit it."
Pandemic Possibilities?
The appearance of the new strain in urban locations is particularly troubling to virologists, who fear that the vaccine-resistant virus could ignite a pandemic if it mutates to become easily transferred from human to human.
"If you have a situation with large numbers of poultry that are poorly vaccinated, close human-to-poultry contact, and infected birds moving around the country—you're just asking for additional viruses to evolve," Ip said.
So far no evidence has been found to suggest that any strain of H5N1—including the Fujian-like type—can be passed easily from human to human.
But the University of Hong Kong's Guan fears the rapid spread of the strain may still pose a threat.
"We think that this virus is likely to have already instigated a third wave of H5N1 infection in this region, as it is already widespread in southern China and has also been detected in other neighboring countries," he said.
"However, as of yet, we do not have any evidence that it is causing widespread infection outside of our surveillance area."
New Strategies
Asian heath care officials may have to modify their anti-bird flu systems in order to prevent the new strain from sweeping through the region's poultry populations and posing potential problems for human health.
"Current control measures are ineffective in dealing with the evolutionary changes that H5N1 undergoes," Guan said.
"This study also suggests that reliance on a single vaccine against H5N1 over a number of years, which is currently practiced, is unlikely to adequately control this disease in poultry."
USGS's Ip echoes Guan's belief that a vaccination program by itself is not a complete solution.
"I think that in this particular case the authors make a convincing argument that the vaccine may not be the best match against the virus in circulation," he said.
"You need to have a comprehensive program that monitors which flocks are infected and deals with them, stops the movement of infected animals, and provides timely access to information."
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how about a nice hot steaming bowl of STFU!

00110001 00110011 01101011 and damn proud of it!

Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 11-01-2006, 04:08 PM curdledvomit is offline  
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#848  

tek000
 
We knew this already, happened long ago with china vaccinating tons of birds.
Old 11-01-2006, 05:32 PM tek000 is offline  
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curdledvomit
 
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this from http://www.bloomberg.com/apps/news?p...vQ&refer=japan


Two Bird Flu Gene Mutations Might Lead to Faster Human Spread


By John Lauerman
Nov. 15 (Bloomberg) -- Two mutations in a gene of the bird flu virus may have put it on the path to becoming more contagious among humans, scientists said.
The gene controls how the virus attaches to cells in breathing passages, said researchers led by Shinya Yamada, a University of Tokyo virologist who led the research, published today in the journal Nature. The gene changes allow the virus to attach more easily to surface molecules, called receptors, on human cells, the researchers said.
Yamada's team found the mutations in strains of the virus taken from chickens and people in 2004, 2005 and early 2006 that didn't cause widespread human outbreaks of flu. The bird virus, called H5N1, will have to undergo more adaptation to start spreading quickly in people, said study co-author John Skehel, retired director of the National Institute for Medical Research in London.
``We need to follow these mutations and see whether they come up again in other viruses isolated from humans,'' Skehel said yesterday in a telephone interview. ``That might give some indication as to whether they were involved in transfer of the virus to humans.''
The researchers analyzed variations in the H5N1 hemagglutinin gene, which makes a protein that allows the virus to enter cells and is responsible for its most lethal effects. The protein fuses the influenza virus to the surface of the cell, rips open the cell wall and allows the viral genetic material to flow in and take over the cell.
Pandemics
Most H5N1 viruses prefer to bind to a bird receptor molecule. The U.K. and Japan researchers found that the mutations at two places in the gene, identified as 182 and 192, allow the virus to bind to both bird and human receptors.
Human flu viruses that caused pandemics in 1957 and 1968 also differed from closely related bird viruses at just two points on a similar gene, Skehel said. More study is needed to determine how much difference the changes in the H5N1 gene make in its ability to attack human cells, he said.
``We know they can bind human receptors,'' Skehel said. ``The question is how well they can bind.''
Monitoring such hot spots in samples of H5N1 may help give early warning of a pandemic threat, said Albert Osterhaus, head of virology at the Erasmus Medical Center in Rotterdam.
``It's definitely something to be on the lookout for,'' said Nov. 13 in a telephone interview. Still, he said, more genetic changes will be necessary to allow the virus to begin spreading in people.
``The receptor usage is not the only thing,'' Osterhaus said. ``Probably more than that needs to happen for the virus to become pandemic.''
Infections
H5N1 has infected 258 people and killed 153 of them since late 2003, the World Health Organization said Nov. 13. The virus might kill millions worldwide if it gains the ability to spread quickly in people, like the virus that caused the 1918 pandemic that killed as many as 50 million people.
Almost half the total human deaths from H5N1, 75, have occurred this year alone. Still, researchers have said there is no evidence the virus has become contagious among people. That makes it difficult to know whether the mutations found by the Japan and U.K. researchers make a pandemic more likely, said Peter Palese, a microbiologist at Mount Sinai School of Medicine in New York who studies bird flu.
``These viruses are mutating all the time and it's not clear they've gained any ability to be better transmitted,'' Palese said Nov. 13 in a telephone interview. ``These viruses have had a chance, and they haven't done it.''
To contact the reporter on this story: John Lauerman in Boston at jlauerman@bloomberg.net .
Last Updated: November 15, 2006 13:07 EST
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Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 11-15-2006, 02:55 PM curdledvomit is offline  
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why the fuck was this unlocked


NOTHING IS GOING TO HAPPEN
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Old 11-15-2006, 02:55 PM growler is offline  
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WORDS!!
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Old 11-15-2006, 02:55 PM camelmix is offline  
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curdledvomit
 
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[quote=popnfresh6298;19927976]why the fuck was this unlocked


snipquote]


cause it is informational and if you don't like it don't click.

go be cute in the KC
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how about a nice hot steaming bowl of STFU!

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Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 11-15-2006, 03:04 PM curdledvomit is offline  
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you are reaching JoePits levels of paranoia
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Old 11-15-2006, 03:14 PM Tenacious N is offline  
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Quote:
Originally Posted by Tenacious N View Post
you are reaching JoePits levels of paranoia

Who said I was parinoid? I mean its in the news every day, Fox,ABC,NBC,CBS,CNN...pick a channel.

I am just passing on what I think is important for people to know , and Lord knows this place needs help.
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how about a nice hot steaming bowl of STFU!

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Squid posted..."curdledvomit is the first +10k guy i actually care about"

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Old 11-15-2006, 03:16 PM curdledvomit is offline  
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